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In this issue:

1. Share Success: Letters From Readers
2. Research News: Diabetes-Linked Kidney Cancer Risk Different in Men and Women
3. Useful Links
4. What Are Others Saying About EZorb and Marvlix?

Letter I: From Roxane H.
Received at sharesuccess @ ezorbonline.com Wed, Sep 28 at 12:30 PM
(Unedited)

Subject: In Response to Caroline C's ezorb review (Issue 345, September 28, 2022)

Caroline, I totally agree with you. I tell all my friends and family about eZorb but they do not believe and do not want to pay the expense.

I had been looking for something/anything for a very long time to heal my heel spurs. I did much research, and came across eZorb. Though the cost was higher than I would have liked I tried it as my heel spurs were causing me to not be as active as I like (I'm only 55 so sitting on the sidelines wasn't an option LOL).

I've been taking this for so long that I don't remember exactly when it cured my spurs, but I've noticed other things that improved as well (less joint pain, etc.).

After about a year on eZorb I decided to add Marvlix to my daily routine. It would be great if HealthCare insurance would start recognizing this as medicine. I'm convinced I don't have to take prescription drugs because I take these 2 products.

Hopefully I will always be able to afford as I wouldn't want to live without this stuff. Do wish that others could see the long term benefit of potential less hospital/clinic visits along with less prescription meds.

Take care, and God Bless this company for producing two outstanding products for our health!

Letter II: From Kathy G.
Voice Mail Received by Medical Staff Thu, Oct 20 at 12:50 PM
(Unedited)

Good morning, this is Kathy G. I live in Arizona. I talked with you probably in April and May. I need to report to you that I've been on EZorb as you prescribed 4 in the morning 4 at night.

Because I'd been on Prolia and haven't taken them for about a year. So I just now had my bone density results. And they are the same. So I think EZorb must be working very well. And I'm so happy because osteoporosis is my culprit.

Thank you so much for explaining all to me. Please call me if you like. My cell phone is 386-xxx-xxxx. Once again my name is Kathy G., in Arizona.

Our newsletter reaches over 200,000 subscribers worldwide. Success stories you shared in the past have made a great impact on many people's life.

Please email your story to sharesuccess @ ezorbonline.com or simply post it to Testimonial Submit Form. Your personal information will never be revealed to the public.

Diabetes has a stronger association with the risk for kidney cancer in women than men, despite men being overall more likely to develop the malignancy, shows a nationwide cohort study from Korea.

Jay Shen (University of Nevada, Las Vegas, USA) and colleagues looked at data from more than 5 million men and 4 million women who took part in the South Korean national health screening program in 2009. None of these people had a history of cancer or were diagnosed with it within 1 year of baseline, but during follow-up to the end of 2018, there were 12,381 cases of kidney cancer in this population.

The incidence rate was higher in men than women, irrespective of smoking status. For example, in never smokers the rates of kidney cancer per 100,000 person-years were 17.8 and 8.5 in men and women with normoglycemia, respectively, and the corresponding rates in those with diabetes were 38.2 and 19.0.

In both sexes, impaired glucose metabolism (based on fasting plasma glucose) was associated with higher rates of kidney cancer. However, after adjusting for factors such as age, alcohol consumption, and BMI, the effect was more prominent in women than men.

Specifically, in never smokers, women with prediabetes had a significant 19% increased risk for kidney cancer and those with diabetes had a 34% increased risk, whereas the corresponding risk increases in men were a nonsignificant 6% and a significant 25%.

The findings were similar in ever smokers, although the relative risk increase associated with impaired glucose metabolism was somewhat larger. Compared with never smokers with normoglycemia, the risk increases associated with prediabetes and diabetes in women who had ever smoked were 56% and 85%, respectively, and in men they were 22% and 49%.

This was despite the absolute incidence rates of kidney cancer being no higher in ever smokers than never smokers, although the adjusted risk was slightly higher in male ever smokers, by 12%.

“Although kidney cancer is predominant in men, women with prediabetes are at an increased risk of kidney cancer,” write the researchers in Diabetes Care.

“This finding should not be overlooked during the monitoring of individuals with hyperglycemia for kidney complications.”

And they add that “given the increasing incidence of kidney cancer, particularly in the younger population, adequate management of diabetes and prediabetes may help to reduce the risk of developing kidney cancer.”

Original research was published in Diabetes Care 2022; doi:10.2337/dc22-0961.

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