Berl Munch Tierarztl Wochenschr 1999 Oct-Nov;112(10-11):400-6
Efficacy and tolerance of a calcium-magnesium-aspartate solution in the treatment of hypocalcemic parturient paresis in cows
[Article in German]
Andresen U, Kietzmann M, Andresen P.
Institut fur Pharmakologie, Toxikologie und Pharmazie, Tierarztlichen Hochschule Hannover.
The systemic tolerance of a solution of calcium aspartate and magnesium aspartate was studied in 7 cows.
Intravenously administered dosages of 500 ml per cow were well tolerated. A twofold increase of the serum calcium concentration was measured. In 2 cows which were treated with 1000 ml of the solution a threefold increased calcium concentration and heart arrhythmia were found.
The clinical efficacy of the solution was demonstrated in a study with 44 hypocalcemic cows. A long lasting increase of the serum calcium as well as an enhanced phosphorus concentration were measurable.
In conclusion, the calcium-magnesium-aspartate solution seems to be an efficacious and well tolerated alternative for the treatment of hypocalcemia in cows.